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Tuesday, 23 June 2015

Donor Oocyte Programme

Welcome to the donor egg programme, which has been functioning since 2002.  the donor oocyte (egg) programme is a boon for women who are unable to produce healthy oocytes or who have chromosomal abnormalities or who have had repeated IVF failures.  The selection criteria for donors abide by strict guidelines laid down by Human Fertilization and Embryology act and by the guidelines laid down by American Society of Reproductive medicine.  PFRC has a large donor bank with over 150 donors.

Egg Donation:
The programme is one of the largest in India and provides quality service at affordable cost.  Worldwide couples have benefited by this programme and are immensely happy with the professional service offered by the center.

Egg Donation and you:
Our egg donation program at Conceptual Options allows Intended parents to choose a donor with the physical and mental characteristics that match their own.  The eggs from this donor are then fertilized with the sperm provided by the partner or a donor and transferred into either a surrogate or the intended mother.

Selection criteria include for the Donor:

    Age less than 27
    Must have had children earlier
    Should undergo all medical tests for general health
    Normal hormone values and normal uterus and ovaries
    No history of genetic or medical problems.
   Donors are not allowed to donate no more than 6 times.  The donors are counseled regarding the procedure and the importance of daily visits to the clinic.  They are subjected to psychological assessment and we ensure that they stick to unit protocols to ensure smooth functioning of the programme.
For the children:

The children also undergo medical and psychological IQ assessment to ensure quality care.  A database of physical characteristic, medical screening and all assessments made is maintained and the donor is matched as per the requirement of the recipient. Consent forms are signed by the donor, her husband and the recipient couples to avoid legal problems.
We have a programme for oocyte donation for women with premature ovarian failure, surgical or induced menopause and those in the perimenopausal group.  Some women with repeated poor recruitment of follicles at the time of IVF, women with extensive endometriosis, severe pelvic adhesions and in accessible ovaries might also qualify for this programme.  A total of 506 babies have been delivered till date.  The success rate of the donor oocyte program is 65 – 69%.  Their babies are as normal as other babies born through IVF programs using own oocytes.

Egg Donation Program:

Clinical Pregnancy rate per Embryo Transfer                67%
Clinical Pregnancies                                                      55%

Donor Egg Cycle:

In this cycle you do not undergo ovarian stimulation. The eggs are taken from a donor who undergoes ovarian stimulation after down regulation as explained in the long protocol.  You will be asked to take T. Ovral G from a specific day and stop on a specific date.  Injection suprefact is started before Ovral G is stopped for down regulating your body hormones.  You have to come daily for the injections.  On Day 3 of the period you have to undergo an ultrasound to measure the Endometrial thickness, if it has been sufficiently suppressed, tab.  Progynova is started from D3 to stimulate Endometrial growth.  The Endometrial thickness is measured on frequent scans and when the lining is about 1 cm and eggs have been collected from the donor your husband is asked to give a semen sample (on the day of egg collection from the donor).  Fertilization is done.  You will be asked to stop suprefact injection and start inj.  Gestone 100 mg.  daily from that day.  You should call the unit the next day to find out about the day of embryo transfer.
Regarding the donor, we select a healthy person in the age group of 20-25.  We screen them for major infections like VDRL, Hbs Ag & HIV.  Detailed family history, medical history & surgical history is enquired into.  We select people who already have healthy children so that we can rule out major familial diseases.  Confidentiality is maintained.  The 2-3% risk of congenital anomalies found in the general population is applicable here also.

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